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    Item type:Publication,
    Serious Games Created for Cognitive Rehabilitation: A Systematic Review
    Cognitive rehabilitation is a process by which people who have suffered some type of brain impairment recover their mental abilities. This type of treatment has classically been carried out with concrete materials of pencil and paper, however, currently the use of technology has provided a significant contribution to improve the motivation and interest of patients involved in this process. In this research, a systematic review of the main studies that have generated some type of technology for the cognitive stimulation and rehabilitation process was carried out. In the collection of studies, 24 published articles were found that allowed understanding aspects such as sample size, age, gender, countries, continents, type of interventions and the main technological developments that have been developed in recent years in favor of cognitive stimulation and rehabilitation. The results are discussed in relation to the importance of conducting this type of studies in favor of the treatment processes and the need to improve the quality of the treatment process
      20
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    Item type:Publication,
    Effects of a dual intervention (motor and virtual reality-based cognitive) on cognition in patients with mild cognitive impairment: a single-blind, randomized controlled trial
    (2024) ; ;
    Carolina Del-Valle-Soto
    ;
    ;
    Guillermo Palacios-Navarro
    <jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>The increase in cases of mild cognitive impairment (MCI) underlines the urgency of finding effective methods to slow its progression. Given the limited effectiveness of current pharmacological options to prevent or treat the early stages of this deterioration, non-pharmacological alternatives are especially relevant.</jats:p> </jats:sec><jats:sec> <jats:title>Objective</jats:title> <jats:p>To assess the effectiveness of a cognitive-motor intervention based on immersive virtual reality (VR) that simulates an activity of daily living (ADL) on cognitive functions and its impact on depression and the ability to perform such activities in patients with MCI.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>Thirty-four older adults (men, women) with MCI were randomized to the experimental group (<jats:italic>n</jats:italic> = 17; 75.41 ± 5.76) or control (<jats:italic>n</jats:italic> = 17; 77.35 ± 6.75) group. Both groups received motor training, through aerobic, balance and resistance activities in group. Subsequently, the experimental group received cognitive training based on VR, while the control group received traditional cognitive training. Cognitive functions, depression, and the ability to perform activities of daily living (ADLs) were assessed using the Spanish versions of the Montreal Cognitive Assessment (MoCA-S), the Short Geriatric Depression Scale (SGDS-S), and the of Instrumental Activities of Daily Living (IADL-S) before and after 6-week intervention (a total of twelve 40-minutes sessions).</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>Between groups comparison did not reveal significant differences in either cognitive function or geriatric depression. The intragroup effect of cognitive function and geriatric depression was significant in both groups (<jats:italic>p</jats:italic> &lt; 0.001), with large effect sizes. There was no statistically significant improvement in any of the groups when evaluating their performance in ADLs (control, <jats:italic>p</jats:italic> = 0.28; experimental, <jats:italic>p</jats:italic> = 0.46) as expected. The completion rate in the experimental group was higher (82.35%) compared to the control group (70.59%). Likewise, participants in the experimental group reached a higher level of difficulty in the application and needed less time to complete the task at each level.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusions</jats:title> <jats:p>The application of a dual intervention, through motor training prior to a cognitive task based on Immersive VR was shown to be a beneficial non-pharmacological strategy to improve cognitive functions and reduce depression in patients with MCI. Similarly, the control group benefited from such dual intervention with statistically significant improvements.</jats:p> </jats:sec><jats:sec> <jats:title>Trial registration</jats:title> <jats:p>ClinicalTrials.gov NCT06313931; <jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="https://clinicaltrials.gov/study/NCT06313931">https://clinicaltrials.gov/study/NCT06313931</jats:ext-link>.</jats:p> </jats:sec>
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