This study proposes a practical model to evaluate the usability of cloud-based ERP systems. The proposed model involves quantitative and qualitative methods, that is, we propose a mixed-methods approach that includes four dimensions: customized heuristics assessment with usability experts, use of automated tools, usability testing with users, and social factors assessment with organizational experts. This novel model differs from others in that it incorporates social factors into the usability assessment, recognizing the broad impact of the technology on the organization and vice versa. This last dimension ensures that the proposed usability assessment model is more relevant than traditional models in real business environments. The viability of the proposed model was demonstrated by providing case study results.