The global population of individuals with disabilities, representing 15% of the world’s people, faces significant challenges in accessing higher education due to insufficient accessibility and persistent discrimination. This paper aims to evaluate the integration of artificial intelligence (AI) and assistive technologies in higher education to improve learning experiences for students with disabilities. Despite advancements in AI, only a small proportion of students with disabilities report satisfaction with existing inclusion efforts. Through a systematic review of the scientific literature from 2019 to 2023, this study examines the current use of AI in higher education, focusing on its application to enhance accessibility, personalized learning, and support for students with disabilities. The research highlights key areas such as intelligent tutoring systems, adaptive learning, and the role of educational technologies in fostering inclusion. While AI and assistive technologies hold great potential, challenges including ethical concerns, biases, and the low adoption rate of assistive technologies remain. The findings emphasize the need for further research to ensure that AI fosters genuine inclusion rather than exacerbating exclusion, urging continued efforts in developing more accessible educational environments for all students.