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U-Net Models for Breast Cancer Detection: Improving Diagnostic Accuracy and Specificity

2024 , Dayanara Yánez-Arcos , Ayala-Chauvin, Manuel Ignacio , Elena Blanco-Romero

Breast cancer remains a critical global health issue, necessitating continuous research and innovative approaches for diagnosis, treatment, and prevention. This study evaluates the effectiveness of U -Net models in enhancing diagnostic precision and efficiency using real hospital samples. We aim to improve key diagnostic metrics such as accuracy, sensitivity, and specificity through the application of U-Net models. Our image classification model, tailored for 256 × 256 × 3 input images, excels in detecting and categorizing tumor cells. The architecture begins with initial convolutional layers featuring 64 filters, progresses to layers with 128 filters, and includes a Dropout layer to prevent overfitting. The deep network for object detection utilizes both region proposal and regression/classification approaches, achieving 92.27% confidence and 100% accuracy. Additionally, our deep learning algorithms accurately segment nuclei in histopathological images, employing a clustering strategy that delivers 88.81% confidence and 100% accuracy. Visual results demonstrate precise tumor cell localization and prediction confidence. Performance metrics from ten experimental runs indicate average confidence levels between 74.19% and 92.31%, with 90.0% accuracy and specificity in benign analysis. The model's ability to classify non-carcinomas versus carcinomas achieved an AUC of 0.78, illustrating its effective differentiation between classes

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Design of a Gravity Ropeway in Nepal: A Methodological Analysis for Appropriate Technologies

2024 , Elena Blanco-Romero , Carles Domènech-Mestres , Ayala-Chauvin, Manuel Ignacio

This article describes the complete development of a design project for a context-integrated appropriate technology, a gravity ropeway for transporting agricultural products in remote areas of Nepal. The main purpose was to improve and optimize existing gravity ropeway designs, prioritizing simplicity, safety, and local manufacturability and maintenance. The design process followed a phased methodological approach used in machine design, which included stages of definition, conceptual design, materialization, and detailed design. The results of the ropeway installation demonstrate a reduction in the time and effort required by farmers to transport their products, consequently leading to a significant improvement in their quality of life. Despite the methodology followed, deficiencies were identified in the project execution procedure: lack of documentation and lack of explicit consideration of the local context in the design specifications, which could compromise the continuity and success of the project. This analysis highlights the need to adapt traditional design methodologies to appropriate technology projects. Specific procedures that address the characteristics of the local environment should be included to integrate the design into the context and accurately determine the needs of users in development projects.

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Publication

U-Net Models for Breast Cancer Detection: Improving Diagnostic Accuracy and Specificity

2024 , Dayanara Yánez-Arcos , Ayala-Chauvin, Manuel Ignacio , Elena Blanco-Romero

Breast cancer remains a critical global health issue, necessitating continuous research and innovative approaches for diagnosis, treatment, and prevention. This study evaluates the effectiveness of U -Net models in enhancing diagnostic precision and efficiency using real hospital samples. We aim to improve key diagnostic metrics such as accuracy, sensitivity, and specificity through the application of U-Net models. Our image classification model, tailored for 256 × 256 × 3 input images, excels in detecting and categorizing tumor cells. The architecture begins with initial convolutional layers featuring 64 filters, progresses to layers with 128 filters, and includes a Dropout layer to prevent overfitting. The deep network for object detection utilizes both region proposal and regression/classification approaches, achieving 92.27% confidence and 100% accuracy. Additionally, our deep learning algorithms accurately segment nuclei in histopathological images, employing a clustering strategy that delivers 88.81% confidence and 100% accuracy. Visual results demonstrate precise tumor cell localization and prediction confidence. Performance metrics from ten experimental runs indicate average confidence levels between 74.19% and 92.31%, with 90.0% accuracy and specificity in benign analysis. The model's ability to classify non-carcinomas versus carcinomas achieved an AUC of 0.78, illustrating its effective differentiation between classes.

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Publication

Performance and Real-World Variability of Predictive Maintenance Models for Vehicle Fleets

2024 , Avilés-Castillo, Fátima , Dayanara Yánez-Arcos , Ayala-Chauvin, Manuel Ignacio , Elena Blanco-Romero

This study presents a comprehensive evaluation of predictive maintenance models for vehicle fleets, detailing a sequence of systematic steps to ensure model performance and address real-world variability. The process begins with database creation and data preprocessing, where relevant maintenance records are filtered, and datetime columns are converted to facilitate time-based calculations. Grouping and aggregation techniques are then applied to count occurrences of specific maintenance activities and identify common failure types. For model training, we define a neural network architecture comprising dense and dropout layers to mitigate overfitting, compile the model with suitable loss functions and optimizers, and train it using the prepared data. The trained model, along with the scaler and encoder, is saved for future use. To augment the dataset, synthetic data is generated using the Faker library and random distributions, with added noise to mimic real-world variability. Preprocessing steps are reapplied to this synthetic data to ensure consistency. By implementing this neural network, we achieved a sensitivity of 0.93 and an ROC of 0.71. Following these detailed steps, we develop a robust predictive maintenance model that effectively identifies failures and non-failures, ultimately enhancing the reliability and efficiency of vehicle fleet management.