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Hot flashes: a potential marker of deterioration of health-related quality of life
(2026)
Juan E. Blümel
;
María S. Vallejo
;
Peter Chedraui
;
Eugenio Arteaga
;
Félix Ayala
Objective: Hot flashes are among the most common symptoms of the menopausal transition and have traditionally been considered benign and self-limiting. However, increasing evidence suggests that they may indicate broader neurovascular and inflammatory dysregulation linked to reproductive aging. The possible effect of hot flush severity on health-related quality of life (HRQoL) remains inadequately studied, particularly in Latin American populations. This study aimed to examine the association between hot flash severity and HRQoL in middle-aged women using validated tools and a large, multicenter sample. Method: A cross-sectional study was conducted between June 2024 and January 2025 in 30 healthcare centers across 12 Latin American countries. A total of 3523 women aged 40–60 years were assessed using the Menopause Rating Scale (MRS) to evaluate vasomotor symptoms and the Short Form-36 Health Survey (SF-36) to measure HRQoL. Multivariable logistic regression models were utilized to estimate the association between hot flush severity and low HRQoL, adjusting for sociodemographic, behavioral and clinical covariates. Results: Increasing severity of hot flushes was significantly associated with lower HRQoL scores across all SF-36 domains. In the logistic regression analysis, mild hot flushes (MRS item 1 score = 1) were associated with increased odds of impaired HRQoL (odds ratio [OR] 1.29; 95% confidence interval [CI]: 1.08–1.55), whereas very severe symptoms (MRS item 1 score = 4) demonstrated a substantially stronger association (OR 4.10; 95% CI: 2.93–5.74). Additional factors significantly associated with lower HRQoL included physical inactivity, the presence of comorbidities, obesity, current use of psychotropic medication, age ≥50 years and having two or more children. Conclusion: Hot flush severity is a strong and independent determinant of HRQoL in midlife women. These findings underscore the need for systematic assessment and targeted management of vasomotor symptoms in routine care, supporting the hypothesis that hot flashes may be a clinical marker of systemic aging. © 2026 International Menopause Society.
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Health as a Determining Factor in Economic Progress and Living Conditions in Ecuador
(2024)
Morales Molina, Tania
;
Chabely Figueredo-Morales
;
Ximena Morales-Urrutia
;
Geri Belén Bucheli-Vásquez
The contributions of health in economic progress contribute to the improvement of people’s living conditions and is a determinant in sustained growth to provide advances and improvements in living standards. The objective of the research is to demonstrate how economic capital truly intervenes in the social behavior and living conditions of people, especially in those areas where the population is more vulnerable. A descriptive observational study was conducted from January to July 2023 in the parish of Quisapincha (rural sector), province of Tungurahua, Ecuador. The population consisted of 11,581 people and the sample consisted of 116 people chosen by non-probabilistic convenience sampling. A structured questionnaire was applied personally to collect the data. The results denoted that the economic capital and environment of a country represent a future prognosis in the economic coverage to ensure education, health, food, personal privileges that improve the lifestyles of individuals and their families. The results of this research can be useful to evidence the project of local public policies that collaborate to the prevention of diseases as a determining factor in the economic progress and living conditions of individuals in Ecuador
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