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Item type:Publication, Obesity-focused dietary interventions in breast cancer care: A comprehensive review of medical nutrition therapy approaches and efficacy in prevention and treatment(2026); Luigi BarreaObesity is associated with an increased risk of developing breast cancer, particularly in postmenopausal women, through mechanisms such as excessive estrogen production, insulin resistance, and chronic low-grade inflammation, all of which promote tumor initiation and progression. Alterations in the gut microbiota, frequently observed in obesity, further exacerbate this risk by influencing estrogen metabolism, modulating immune responses, and promoting systemic inflammation, thereby creating a microenvironment conducive to breast cancer growth. Medical nutrition therapy plays a crucial role in managing these interrelated conditions, with dietary interventions such as the Mediterranean diet, ketogenic diet, and intermittent fasting showing potential to reduce weight, improve metabolic health, modulate the gut microbiome, and positively influence inflammatory and hormonal signaling. While short-term outcomes are promising, long-term studies are required to confirm their effects on breast cancer survival and recurrence. Personalized nutrition—accounting for genetic, epigenetic, and microbiome profiles—is emerging as a highly effective approach to enhance therapeutic outcomes. Integrating targeted nutritional strategies into breast cancer treatment protocols is essential to improve prognosis, optimize therapy responses, and enhance patients’ quality of life. This narrative review examines the role of nutritional therapies in the prevention and management of obesity and breast cancer, emphasizing their impact on tumor biology, treatment efficacy, and patient health. © 2026 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license. http://creativecommons.org/licenses/by-nc-nd/4.0/3 - Some of the metrics are blocked by yourconsent settings
Item type:Publication, Contemporary Strategies and Trends in Nursing Care for Women with Breast CancerHER2-positive breast cancer, one of the most aggressive forms of this disease, presents significant therapeutic challenges due to its complexity and high recurrence. Subcutaneous therapies, such as trastuzumab and pertuzumab, have improved treatment efficacy and patient quality of life, but pose challenges for nursing professionals in patient education, prevention of complications, and use of remote monitoring technologies. This study reviewed literature from 2015 to 2024 in databases such as PubMed, Scopus, APA PsycNet, Scielo, and Web of Science to analyze advances in the management of subcutaneous therapies and nursing care. The findings confirm that subcutaneous administration of trastuzumab and pertuzumab is safe and well tolerated, reducing complications compared to traditional methods, especially when using devices such as PICC catheters and subcutaneous ports. The integration of telemedicine and remote monitoring allowed for improved adherence, minimized complications, and optimized resources. Furthermore, ongoing training of nursing staff was identified as essential for effective management of devices and fostering patient autonomy. This review underlines the importance of integrating technologies and education into public health policies to address emerging issues in breast cancer management, especially in vulnerable populations with limited access to services. This review was registered in the Open Science Framework (OSF). (Registration number: DOI: 10.17605/OSF.IO/KWPC9)33