This study examines the relationship between the Latin American Artificial Intelligence Index (ILIA) and the Web Accessibility Index (WAIN) in 19 Latin American countries to evaluate how technological innovation aligns with digital inclusivity. Results reveal notable disparities: Uruguay, Chile, and Brazil excel in both indices, whereas Jamaica and Venezuela face critical challenges. Significantly, high scores in artificial intelligence adoption do not always correlate with improved web accessibility, underscoring the need for integrated strategies that prioritize compliance with the Web Content Accessibility Guidelines (WCAG) 2.2 and inclusive design. The research highlights accessibility as a fundamental pillar for sustainable digital ecosystems and equitable access to technology. Limitations include the regional focus on Latin America, the reliance on automated tools, and the dynamic nature of technology. Future research should incorporate longitudinal analyses, user-centered evaluations, and comparative studies across diverse regions to develop comprehensive frameworks that are grounded in empirical evidence. By aligning technological progress with inclusivity, this study emphasizes the importance of fostering sustainable and accessible digital environments. Recommendations include adopting accessibility standards in early development stages, enhancing public policy, and prioritizing universal design. These steps are essential to achieving the Sustainable Development Goals (SDGs) related to reducing inequalities and promoting inclusive institutions. This work is a foundation for advancing equitable digital ecosystems in Latin America.